Figure 2.

Mitochondria regulate signaling. Mitochondria regulate signaling pathways through release of cytochrome c to invoke caspase-dependent cell death, release of reactive oxygen species (ROS) to induce gene expression, and the use their outer membranes as a scaffold for signaling complexes, notably immune responses and control of cell death.

Chandel BMC Biology 2014 12:34   doi:10.1186/1741-7007-12-34
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