Additional file 3: Figure S3.
Disrupted epithelial cells in awd mutant clone show abnormal Notch accumulation. Females of the genotype en2.4-Gal4e22c, UAS-flp/+; FRT82B/FRT82B, awdj2A4 were dissected and the egg chambers were stained for DNA (DAPI), Awd, NICD, and Avl as indicated. Abnormal Notch accumulation in large vesicles is observed in pile-up mutant epithelial cells (arrows), which co-localize with the early endosomal marker Avl (see also Additional file 5: Figure S5A,A’). Bar is 20 μm.
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Ignesti et al. BMC Biology 2014 12:12 doi:10.1186/1741-7007-12-12