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Open Access Commentary

Brain H2A.Z: the long and the short

Juan Ausió

Author Affiliations

Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC V8W 3P6, Canada

BMC Biology 2013, 11:84  doi:10.1186/1741-7007-11-84

Published: 17 July 2013

Abstract

The role of histone variants and their specific post-translational modifications (PTMs) in the epigenetic regulation of gene expression is still poorly understood. A paper published by Simonet and colleagues in Epigenetics and Chromatin describes a new H2A.Z subtype that is specific for brain and pituitary in the carp and provides additional information about the functional epigenetic complexity of the PTMs associated with histone H2A.Z.

See research article: http://www.epigeneticsandchromatin.com/content/6/1/22 webcite