p53 transcriptional activity and its effect on cell fate. (a) Gene expression of a set of well-known p53 target genes by real-time quantitative (q)PCR analysis in U-2 OS cells treated with 1 μmol/l (filled columns) and 100 μmol/l (empty columns) etoposide, respectively. Error bars show standard deviations of data from three independent experiments. (b) Comparison of expression of selected p53 target genes by western blotting analysis.
Chen et al. BMC Biology 2013 11:73 doi:10.1186/1741-7007-11-73