Open Access Open Badges Correction

Correction: the buccohypophyseal canal is an ancestral vertebrate trait maintained by modulation in sonic hedgehog signaling

Roman H Khonsari1152*, Maisa Seppala13*, Alan Pradel4, Hugo Dutel56, Gaël Clément5, Oleg Lebedev7, Sarah Ghafoor1, Michaela Rothova18, Abigael Tucker1, John G Maisey4, Chen-Ming Fan9, Atsushi Ohazama1, Paul Tafforeau10, Brunella Franco11, Jill Helms12, Courtney J Haycraft13, Albert David14, Philippe Janvier5, Martyn T Cobourne13* and Paul T Sharpe1*

Author Affiliations

1 Department of Craniofacial Development and Stem Cell Research, Comprehensive Biomedical Research Center, Dental Institute, King’s College London, London, UK

2 Service de Chirurgie Maxillo-Faciale, Centre Hospitalier Universitaire Hôtel-Dieu, Nantes, France

3 Department of Orthodontics, Dental Institute, King’s College London, Guy’s Hospital, London, UK

4 American Museum of Natural History, New York, USA

5 CNRS-UMR 7207, Muséum national d'histoire naturelle-UPMC, Paris, France

6 CNRS-UMR 7179, Muséum national d'histoire naturelle, Paris, France

7 Paleontological Institute of Russian Academy of Science, Moscow, Russian Federation

8 Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic

9 Department of Embryology, Carnegie Institution of Washington, Baltimore, USA

10 European Synchrotron Radiation Facility, Grenoble, France

11 Department of Pediatrics, Università degli Studi di Napoli Federico II, Naples, Italy

12 Department of Surgery, Stanford University, Palo Alto, USA

13 College of Dental Medicine, Craniofacial Biology, Medical University of South Carolina, Carolina, USA

14 Service de Génétique clinique, Centre Hospitalier Universitaire Hôtel-Dieu, Nantes, France

15 Department of Craniofacial Development and Stem Cell Biology Dental Institute, King's College London, Guy's Hospital, London, SE1 9RT, UK

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BMC Biology 2013, 11:70  doi:10.1186/1741-7007-11-70

The electronic version of this article is the complete one and can be found online at:

Received:13 June 2013
Accepted:13 June 2013
Published:21 June 2013

© 2013 Khonsari et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The authors noted that the figure legend for Figure 1 (parts (a) and (b)) needs correcting [1].

The Figure 1 legend should read:

Figure 1

Rathke’s pouch is located at a triple boundary. a) Whole-mount LacZ staining of an R26R-Sox17-Cre E10.5 mouse embryo showing the anterior limit of the endoderm (red arrowhead) and the posterior border of Rathke’s pouch (blue arrowhead); endobuccal view of the oral roof. (b) Posterior limit (arrowhead) of the neural crest-derived mesenchyme in the mid-sagittal plane at E12.5, corresponding to the location of the closing buccohypophyseal canal, in an R26R-Wnt1-Cre mouse embryo. (c) Anterior limit of the endoderm in the mid-sagittal plane at E10.5 (arrowhead), LacZ staining, R26RSox17- Cre mouse embryo. (d) Anterior end of the notochord (arrowhead), eosin staining, E10.5, wild-type mouse embryo ant, anterior; post; posterior; RP, Rathke’s pouch.

Please also note the contact address for Philippe Janvier should be: 5.CNRS-UMR 7207, Muséum national d'Histoire naturelle-UPMC, Paris, France.


  1. Khonsari RH, Seppala M, Pradel A, Dutel H, Clément G, Lebedev O, Ghafoor S, Rothova M, Tucker A, Maisey JG, Fan CM, Kawasaki M, Ohazama A, Tafforeau P, Franco B, Helms J, Haycraft CJ, David A, Janvier P, Cobourne MT, Sharpe PT: The buccohypophyseal canal is an ancestral vertebrate trait maintained by modulation in sonic hedgehog signaling.

    BMC Biology 2013, 11:27. PubMed Abstract | BioMed Central Full Text | PubMed Central Full Text OpenURL