Table 4

Two-way permutational multivariate analysis of variance (PERMANOVA) results comparing muscle mRNA levels between cold-acclimated and warm-acclimated normal thyroid and hypothyroid fish
Acclimation temperature Thyroid status Acclimation temperature × Thyroid Status
Gene F d.f. P F d.f. P F d.f. P
PGC1α 3.330 1, 34 0.041* 6.454 1, 34 0.001** 4.357 1, 34 0.026*
PGC1β 12.690 1, 34 0.001** 2.677 1, 34 0.09 2.068 1, 34 0.108
PPARδ 5.708 1, 31 0.010* 0.172 1, 31 0.827 2.511 1, 31 0.117
NRF1 5.069 1, 28 0.021* 0.921 1, 28 0.343 0.268 1, 28 0.714
NRF2a 1.434 1, 28 0.239 0.145 1, 28 0.885 1.086 1, 28 0.302
NRF2b 4.108 1, 17 0.045* 0.557 1, 17 0.537 0.060 1, 17 0.948
COX Vb2 1.996 1, 33 0.124 3.786 1, 33 0.029* 7.293 1, 33 0.002**
ATPase A 3.612 1, 27 0.048* 2.260 1, 27 0.099 3.136 1, 27 0.043*
ATPase B 1.948 1, 27 0.148 1.216 1, 27 0.269 5.903 1, 27 0.012*
COX II 12.410 1, 25 0.001** 3.850 1, 25 0.026* 2.478 1, 25 0.079
ATP 8/6 7.221 1, 24 0.004** 8.229 1, 24 0.002** 2.631 1, 24 0.068

Abbreviations: ATPase A, F0F1-ATPase subunit A; ATPase B, F0F1-ATPase subunit B; ATPase 8/6, F0F1-ATPase subunits 8 and 6; COX II, Cytochrome c oxidase subunit 2; COX Vb2, cytochrome c oxidase subunit 5b2; d.f. degrees of freedom; NRF1, Nuclear respiratory factor 1; NRF2a, Nuclear respiratory factor 2a; NRF2b, Nuclear respiratory factor 2b; PGC1α, Peroxisome proliferator-activated receptor γ coactivator 1-α; PGC1β, Peroxisome proliferator-activated receptor γ coactivator 1-β; PPARδ, Peroxisome proliferator-activated receptor δa and δb.

*P<0.05.

**P<0.01.

Little et al.

Little et al. BMC Biology 2013 11:26   doi:10.1186/1741-7007-11-26

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