Table 1

Percentage of genes with signal peptides or transmembrane domains

n

Absence of signal peptides

P

Absence of transmembrane domains

P


Rats

IL genes

65

92.3%

0.003

93.8%

6 × 10-4

NIL genes

8,410

75.7%

74.6%

Parental genes

637

93.4%

< 10-16

90.1%

< 10-16

Other genes

7,838

74.4%

73.6%

Mice

IL genes

42

95.2%

0.004

92.9%

0.015

NIL genes

8,410

74.6%

75.5%

Parental genes

1,013

91.3%

< 10-16

88.3%

< 10-16

Other genes

7,439

72.5%

73.9%


Absence of a signal peptide or a transmembrane domain indicates mRNA translation on free cytoplasmic ribosomes. Pearson's chi-square test was used to calculate the P values. IL: intron-lost; NIL: no-intron-lost genes; Parental genes: parental genes of processed pseudogenes.

Zhu and Niu BMC Biology 2013 11:23   doi:10.1186/1741-7007-11-23

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