Table 2

High confidence functional targets from miRNA predictions and genome-wide cDNA screen.

miRNAs repressing NF-κB signaling


miRNA

Gene

Transcripts

CS

CSP


miR-24

MYD88

NM_001172569, NM_002468, NM_001172568, NM_001172567, NM_001172566

-0.319

95

RASL11B

NM_023940

-0.35

96

RELA

NM_021975, NM_001145138

-0.307

93

miR-124

TRIM22

NM_001199573, NM_006074

-0.339

96

BECN1

NM_003766

-0.339

96

miR-210

CCNL2

NM_001039577

-0.275

85

miR-491

PLEKHB1

NM_021200, NM_001130033, NM_001130035, NM_001130034, NM_001130036

-0.314

98

TULP3

NM_003324

-0.278

97

TNFSF10

NM_001190943

-0.336

99

miR-506

RELA

NM_021975, NM_001145138

-0.401

98


miRNAs activating NF-κB signaling


miRNA

Gene

Transcripts

CS

CSP


MATN2

NM_030583, NM_002380

-0.351

96

miR-30a

GPR161

NM_153832

-0.298

93

PTGER2

NM_000956

-0.328

95

miR-34b

TLR7

NM_016562

-0.356

98

miR-125b

IKBKG

NM_001099857, NM_001099856, NM_001145255

-0.297

92

MAP3K11

NM_002419

-0.337

95

miR-141

PTGDR

NM_000953

-0.3

97

miR-184

TNK2

NM_001010938, NM_005781

-0.452

94

SLC7A5

NM_003486

-0.306

85

miR-452*

LPAR2

NM_004720

-0.304

95

STMN1

NM_001145454

-0.367

98

NFKBIE

NM_004556

-0.288

94

miR-544

TSPAN13

NM_014399

-0.279

92


CS, context score; CSP, context score percentile; miRNAs, microRNAs; NF-κB, nuclear factor-kappa B. A more negative CS is associated with a more favorable miRNA-mRNA interaction.

Olarerin-George et al. BMC Biology 2013 11:19   doi:10.1186/1741-7007-11-19

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