Table 1

Top hits in -TNF and +TNF screens.

-TNF screen


miRNA

Seed sequence

Fold change

Z-score

P-value


hsa-miR-517c

UCGUGCA

126.3

4.8

0.015

hsa-miR-517a

UCGUGCA

86.2

4.4

0.015

hsa-miR-544

UUCUGCA

37.9

3.6

0.016

hsa-miR-337

CCAGCUC

38.0

3.6

0.016

hsa-miR-452*

CAGUCUC

19.7

3.0

0.018

hsa-miR-326

CUCUGGG

18.8

2.9

0.018

hsa-miR-184

GGACGGA

19.0

2.8

0.019

hsa-miR-34b

AGGCAGU

16.1

2.7

0.019

hsa-miR-483

CACUCCU

12.8

2.5

0.019


+TNF screen


miRNA

Seed sequence

Fold change

Z-score

P-value


hsa-miR-124a

UAAGGCA

-82.8

-4.6

0.015

hsa-miR-452*

CAGUCUC

4.5

1.6

0.015

hsa-miR-483

CACUCCU

6.1

1.9

0.015

hsa-miR-506

AAGGCAC

-22.8

-3.3

0.016

hsa-miR-345

GCUGACU

-22.9

-3.3

0.016

hsa-miR-24

GGCUCAG

-23.7

-3.3

0.016

hsa-miR-375

UUGUUCG

-21.2

-3.2

0.016

hsa-miR-141

AACACUG

3.9

1.4

0.018

hsa-miR-130a

AGUGCAA

3.8

1.4

0.018

hsa-miR-491

GUGGGGA

-15.3

-2.9

0.018

hsa-miR-30a-3p

UUUCAGU

3.9

1.4

0.018

hsa-miR-489

GUGACAU

-13.7

-2.7

0.018

hsa-miR-125b

CCCUGAG

3.5

1.3

0.020

hsa-miR-200b

AAUACUG

3.8

1.4

0.020

hsa-miR-210

UGUGCGU

-9.8

-2.4

0.020


miRNA, microRNA; TNF, tumor necrosis factor.

Olarerin-George et al. BMC Biology 2013 11:19   doi:10.1186/1741-7007-11-19

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