Wnt6 is required for maxillary palp but not wing formation. (A) Wnt6 genomic locus showing the knocked-out region (grey area). (B) Wings from Wnt6KO adult males are not altered in size compared to controls. (C-C’) Wnt6KO wings display grossly normal patterning (C) and no obvious planar-cell polarity phenotype (C’). (D-D”) Wnt6KO flies (D’) lack maxillary palps (positions indicated with arrows). Pan-neuronal re-expression of Wnt6 from a UAS transgene using elav-GAL4 in Wnt6KO animals restores maxillary palp formation (D”). The additional ectopic expression in brain and eye discs causes reduced overall head size and rough eyes. Wnt6KO, Wnt6 knockout.
Doumpas et al. BMC Biology 2013 11:104 doi:10.1186/1741-7007-11-104