Glial GABA and Glu transporters are colocalized. GAT-3 (red) and EAAT2 (green) immunoreactive small puncta surround neuronal cell bodies and dendrites in the CA1 str. pyramidale (top), CA1 str. radiatum (middle) and CA3 str. pyramidale (bottom) regions. GAT-3 and EAAT2 immunoreactivites show almost complete colocalization (yellow) around the soma and on the dendrites of presumable pyramidal cells. Right: higher magnification of boxed region in merged image. R: str. radiatum, P: str. pyramidale, O: str. oriens. Scale bar = 50 μm (GAT-3, EAAT2 and overlay) or scale bar = 10 μM (zoom). All images are Z-projections of 6 optical sections taken at 2 μm distance.
Héja et al. BMC Biology 2012 10:26 doi:10.1186/1741-7007-10-26