|
Sensitivity analysis estimates of cost difference, and the additional number of live birth-producing pregnancies by the estimated cost difference of providing "IUI+IVF" compared to primary offer of IVF, varied sequentially. |
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| Variable varied |
Cost difference £ [("IUI+IVF") - IVF] |
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|
|
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| S-IUI |
1 cycle of IUI |
2 cycles of IUI |
3 cycles of IUI |
4 cycles of IUI |
5 cycles of IUI |
6 cycles of IUI |
|
|
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| LBR = 8.7% |
£43,100 |
£111,900 |
£183,400 |
£257,400 |
£333,800 |
£412,200 |
| LBR varying by cycle order* |
£39,400 |
£114,200 |
£199,500 |
£287,200 |
£379,900 |
£474,400 |
|
|
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| U-IUI |
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|
|
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| LBR = 4.4% |
£0 |
£30,700 |
£62,100 |
£94,100 |
£126,600 |
£159,700 |
| LBR = 2% |
£6,900 |
£45,300 |
£83,700 |
£122,300 |
£161,000 |
£199,900 |
| LBR varying by cycle order± |
£53,800 |
£141,100 |
£233,400 |
£326,800 |
£420,300 |
£514,000 |
|
|
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| C-IUI |
||||||
|
|
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| LBR = 6.6% |
£23,900 |
£76,300 |
£128,900 |
£181,600 |
£234,200 |
£286,800 |
| LBR = 2.5% |
£35,800 |
£102,100 |
£168,400 |
£234,700 |
£301,000 |
£367,300 |
|
|
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| No. of live births expected from full cycles of IVF that could be purchased by the estimated cost difference |
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|
|
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| S-IUI |
||||||
|
|
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| LBR = 8.7% |
3 |
9 |
15 |
20 |
27 |
33 |
| LBR varying by cycle order* |
3 |
9 |
16 |
23 |
30 |
38 |
|
|
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| U-IUI |
||||||
|
|
||||||
| LBR = 4.4% |
0 |
2 |
5 |
7 |
10 |
13 |
| LBR = 2% |
1 |
4 |
7 |
10 |
13 |
16 |
| LBR varying by cycle order± |
4 |
11 |
19 |
26 |
33 |
41 |
|
|
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| C-IUI |
||||||
|
|
||||||
| LBR = 6.6% |
2 |
6 |
10 |
14 |
19 |
23 |
| LBR = 2.5% |
3 |
8 |
13 |
19 |
24 |
29 |
|
* LBR of S-IUI of 10%, 6%, 4%, 4%, 2%, 2% for cycles 1 to 6 respectively ± LBR of U-IUI of 5%, 3%, 2% 2%, 2%, 2% for cycles 1 to 6 respectively. Figures of cost differences are rounded to the nearest hundred. | ||||||
Pashayan et al. BMC Health Services Research 2006 6:80 doi:10.1186/1472-6963-6-80 |
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