Table 3

Serious clinical events with suspicion of cancer recurrence
Serious clinical event characteristics Surgeon-surveillance GP-surveillance Total p value
Surveillance (months) 942 942 1884 ns
Interval SCE 12 13 25 ns
Routine SCE 11 12 23 ns
Total SCE 22 26 48 ns
Symptom initiated SCE
Abdominal pain (n) 3 11 14 0.05
Blood in stool (n) 6 4 10 ns
Anaemia (n) 0 1 1 ns
Weight loss (n) 1 1 2 ns
Lymphadenopathy (n) 2 0 2 ns
Other findings (n) 1 1 2 ns
Total 13 18 31 ns
True cancer recurrence 4 3 7 ns
Test initiated SCE
Elevated CEA 2 4 6 ns
Radiology 6 3 9 ns
Colonoscopy 1 1 2 ns
Total 9 8 17 ns
True cancer recurrence 4 3 7 ns
False positive tests and symptoms (%) 14 (25%) 20 (36%) 34 (31%) ns
Program positive predictive value 0.36 0.23 0.29 ns
Diagnostics for potential recurrent cancer
CEA (repeated) 2 4 7 ns
Chest x-ray 4 3 6 ns
CEUS 2 6 6 ns
Colonoscopy 3 12 15 0.05
CT thorax/abdomen/liver 13 8 21 ns
PET 0 2 2 ns
Consultations 14 23 37 ns
Diagnostic work-up days (SD) 45 (45) 35 (28) 39 (35) ns

PPV: positive predictive value, which is the proportion of positive test/clinical findings that are true positives (i.e., true cancer recurrences). ns: not significant.

Augestad et al.

Augestad et al. BMC Health Services Research 2014 14:137   doi:10.1186/1472-6963-14-137

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