Table 1

Definitions of test and performance characteristics
Gold standard
Yes No
Yes X Y
No Z K
Test/Performance Characteristic Definition Explanation
 Patient Classification, %
  True-Positive X / (No. of Patients) × 100%
  False-Positive Y / (No. of Patients) × 100%
  True-Negative K / (No. of Patients) × 100%
  False-Negative Z / (No. of Patients) × 100%
 Sensitivity, % X / (X+Z) × 100% % of FN hospitalizations correctly identified by claims-based definition
 Specificity, % K / (Y+K) × 100% % of non-FN hospitalizations correctly identified by claims-based definition
 Positive Predictive Value (PPV), % X / (X+Y) × 100% % of hosp. identified as FN hosp. by claims-based definition that were true-positives
 Negative Predictive Value (NPV), % K / (Z+K) × 100% % of hosp. identified as non-FN hosp. by claims-based definition that were true-negatives
 Accuracy, % (X+K) / (No. of Patients) × 100% % of all hospitalizations that were true-positives and true-negatives
 Likelihood ratio positive (LR+) [X/(X+Z)] / [1-K/(Y+K)] Odds of hosp. being an FN hosp. when claims-based algorithm is positive
 Likelihood ratio negative (LR-) [1-X/(X+Z)] / [K/(Y+K)] Odds of hosp. being a non-FN hosp. when claims-based algorithm is negative

FN: febrile neutropenia.

Weycker et al.

Weycker et al. BMC Health Services Research 2013 13:60   doi:10.1186/1472-6963-13-60

Open Data