Table 5

Model comparisons for health outcomes in all-age diabetes cohorts
Cohort 1a (n = 29,058) Cohort 2 (n = 41,925)
Model (df)b c-statisticc(95% CI) cd(%) Brier score LRTe c-statisticc(95% CI) c (%) Brier score LRTe
AMI
Base (7) 0.66 (0.64, 0.68) . 0.02 . 0.68 (0.66, 0.70) . 0.02 .
# diagnoses (10) 0.67 (0.65, 0.69) 0.01 (1.37) 0.02 21.1* 0.68 (0.67, 0.71)* <0.01 (1.47) 0.02 32.1*
Charlson (10) 0.67 (0.65, 0.69) 0.01 (1.52) 0.02 21.5* 0.69 (0.67, 0.71)* 0.01 (1.92) 0.02 37.3*
Elixhauser (35) 0.68 (0.66, 0.69)* 0.02 (2.43) 0.02 44.2* 0.70 (0.68, 0.72)* 0.02 (2.95) 0.02 62.5*
# drugs (10) 0.68 (0.66, 0.69)* 0.02 (2.43) 0.02 36.0* 0.68 (0.66, 0.70) <0.01 (0.88) 0.02 24.1*
CDS (11) 0.67 (0.65, 0.69)* 0.01 (2.28) 0.02 32.8* 0.68 (0.66, 0.70) <0.01 (0.29) 0.02 6.1
Stroke
Base (7) 0.70 (0.68, 0.72) . 0.02 . 0.71 (0.69, 0.72) . 0.01 .
# diagnoses (10) 0.71 (0.70, 0.73) 0.01 (1.57) 0.02 37.8* 0.71 (0.69, 0.73) <0.01 (0.85) 0.01 18.9*
Charlson (10) 0.72 (0.70, 0.73) 0.02 (1.85) 0.02 44.3* 0.71 (0.69, 0.73) <0.01 (0.85) 0.01 17.2*
Elixhauser (35) 0.72 (0.70, 0.74)* 0.02 (2.56) 0.02 45.4* 0.71 (0.69, 0.73) <0.01 (0.85) 0.01 20.6
# drugs (10) 0.71 (0.69, 0.73) 0.01 (0.85) 0.02 19.5* 0.71 (0.70, 0.73) <0.01 (0.99) 0.01 24.2*
CDS (11) 0.71 (0.69, 0.73) 0.01 (1.28) 0.02 33.7* 0.71 (0.70, 0.73) <0.01 (0.99) 0.01 21.2*
LEA
Base (7) 0.65 (0.62, 0.68) . 0.01 . 0.68 (0.65, 0.70) . 0.01 .
# diagnoses (10) 0.71 (0.69, 0.74)* 0.06 (10.36) 0.01 77.4* 0.74 (0.72, 0.77)* 0.06 (9.75) 0.01 128.7*
Charlson (10) 0.74 (0.71, 0.77)* 0.09 (14.06) 0.01 128.4* 0.76 (0.74, 0.79)* 0.08 (12.70) 0.01 201.7*
Elixhauser (35) 0.78 (0.75, 0.81)* 0.13 (20.71) 0.01 305.6* 0.79 (0.76, 0.82)* 0.11 (16.69) 0.01 372.8*
# drugs (10) 0.70 (0.67, 0.72)* 0.05 (7.42) 0.01 53.0* 0.74 (0.72, 0.76)* 0.06 (9.31) 0.01 110.2*
CDS (11) 0.69 (0.66, 0.72)* 0.04 (6.34) 0.01 42.4* 0.72 (0.70, 0.75)* 0.04 (6.65) 0.01 74.5*
ESRD
Base (7) 0.67 (0.63, 0.72) . <0.01 . 0.65 (0.61, 0.69) . <0.01 .
# diagnoses (10) 0.74 (0.70, 0.79)* 0.07 (10.73) <0.01 49.0* 0.77 (0.73, 0.80)* 0.12 (18.52) <0.01 128.0*
Charlson (10) 0.80 (0.76, 0.84)* 0.13 (19.08) <0.01 138.6* 0.82 (0.79, 0.86)* 0.17 (27.01) <0.01 276.6*
Elixhauser (35) 0.84 (0.80, 0.89)* 0.17 (25.78) <0.01 328.6* 0.87 (0.84, 0.90)* 0.22 (34.41) <0.01 555.1*
# drugs (10) 0.73 (0.69, 0.76)* 0.06 (8.20) <0.01 36.6* 0.71 (0.68, 0.75)* 0.06 (9.88) <0.01 50.2*
CDS (11) 0.75 (0.71, 0.79)* 0.08 (12.07) <0.01 61.3* 0.72 (0.68, 0.76)* 0.07 (11.11) <0.01 55.3*
Hospitalization, any reason
Base (7) 0.63 (0.62, 0.64) . 0.24 . 0.63 (0.62, 0.63) . 0.24 .
# diagnoses (10) 0.70 (0.69, 0.71)* 0.07 (11.13) 0.22 2115.1* 0.70 (0.69, 0.70)* 0.07 (11.31) 0.22 3101.3*
Charlson (10) 0.68 (0.67, 0.69)* 0.05 (8.11) 0.23 1424.1* 0.67 (0.67, 0.68)* 0.04 (7.32) 0.23 1794.8*
Elixhauser (35) 0.69 (0.68, 0.69)* 0.06 (9.06) 0.22 1663.7* 0.68 (0.68, 0.69)* 0.05 (8.60) 0.23 2165.5*
# drugs (10) 0.66 (0.66, 0.67)* 0.03 (5.09) 0.23 823.1* 0.65 (0.65, 0.66)* 0.02 (3.98) 0.23 996.2*
CDS (11) 0.65 (0.64, 0.66)* 0.02 (3.50) 0.23 539.2* 0.64 (0.64, 0.65)* 0.01 (2.23) 0.24 503.0*
Hospitalization, diabetes
Base (7) 0.60 (0.59, 0.61) . 0.18 . 0.59 (0.59, 0.60) . 0.15 .
# diagnoses (10) 0.65 (0.65, 0.66)* 0.05 (8.65) 0.18 889.9* 0.66 (0.65, 0.66)* 0.07 (10.83) 0.15 1251.0*
Charlson (10) 0.66 (0.65, 0.67)* 0.06 (9.65) 0.17 1194.1* 0.65 (0.64, 0.66)* 0.06 (9.98) 0.15 1141.8*
Elixhauser (35) 0.67 (0.66, 0.68)* 0.07 (11.65) 0.17 1554.3* 0.66 (0.66, 0.67)* 0.07 (12.35) 0.15 1715.9*
# drugs (10) 0.64 (0.63, 0.64)* 0.04 (5.66) 0.18 524.5* 0.63 (0.62, 0.63)* 0.04 (6.09) 0.15 633.9*
CDS (11) 0.63 (0.62, 0.63)* 0.03 (4.16) 0.18 365.1* 0.62 (0.61, 0.63)* 0.03 (4.57) 0.15 397.7*
Death
Base (7) 0.77 (0.76, 0.78) . 0.08 . 0.79 (0.78, 0.79) . 0.07 .
# diagnoses (10) 0.79 (0.78, 0.80)* 0.02 (3.39) 0.08 499.4* 0.80 (0.80, 0.81)* 0.01 (2.16) 0.07 475.1*
Charlson (10) 0.82 (0.81, 0.82)* 0.05 (6.53) 0.07 1014.0* 0.82 (0.82, 0.83)* 0.03 (4.57) 0.07 1018.0*
Elixhauser (35) 0.83 (0.82, 0.83)* 0.06 (7.96) 0.07 1379.9* 0.84 (0.83, 0.84)* 0.05 (6.10) 0.06 1618.7*
# drugs (10) 0.79 (0.78, 0.80)* 0.02 (2.74) 0.08 429.1* 0.80 (0.79, 0.81)* 0.01 (1.78) 0.07 401.4*
CDS (11) 0.78 (0.77, 0.79)* 0.01 (1.96) 0.08 306.1* 0.79 (0.79, 0.80)* <0.01 (0.89) 0.07 216.9*

aCohort 1 was defined using administrative data from fiscal years 1996/97 to 1997/98 and Cohort 2 was defined using data from 1996/97 to 2001/02; bBase model includes covariates of age, age2, sex, income quintile, geography, and recent diabetes diagnosis, and full models include these variables in addition to the specified comorbidity measure; cA c-statistic with * is significantly different (p < .01) from the c-statistic for the base model, dc = c-statistic for full model minus c-statistic for base model, eA likelihood ratio test (LRT) with * is statistically significant at α = .01; df=degrees of freedom, CDS Chronic Disease Score, AMI Acute Myocardial Infarction, LEA Lower Extremity Amputation, ESRD End-Stage Renal Disease.

Lix et al.

Lix et al. BMC Health Services Research 2013 13:340   doi:10.1186/1472-6963-13-340

Open Data