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Open Access Research article

Frequency, duration and predictors of bronchiolitis episodes of care among infants ≥32 weeks gestation in a large integrated healthcare system: a retrospective cohort study

Valerie J Flaherman1*, Arona I Ragins2, Sherian Xu Li2, Patricia Kipnis23, Anthony Masaquel4 and Gabriel J Escobar25

Author Affiliations

1 Department of Pediatrics, University of California, 3333 California St, Box 0503, San Francisco, CA, 94143-0503, USA

2 Division of Research, Kaiser Permanente Medical Care Program, Systems Research Initiative and Perinatal Research Unit, 2000 Broadway, 2nd floor, Oakland, CA, 94612, USA

3 Kaiser Foundation Health Plan, Inc, Management Information and Analysis, 1950 Franklin St, 17th floor, Oakland, CA, 94612, USA

4 MedImmune, LLC, One MedImmune Way, Gaithersburg, MD, 20878, USA

5 Department of Inpatient Pediatrics, Kaiser Permanente Medical Center, 1425 S. Main St, Walnut Creek, CA, 94596, USA

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BMC Health Services Research 2012, 12:144  doi:10.1186/1472-6963-12-144

Published: 8 June 2012

Abstract

Background

Bronchiolitis is common in the first two years of life and is the most frequent cause of hospitalization in this age group. No previous studies have used an episode-of-care analysis to describe the frequency, duration, and predictors of bronchiolitis episodes of care during the first two years.

Methods

We conducted a retrospective cohort study of 123,264 infants ≥32 weeks gestation born at 6 Northern California Kaiser Permanente hospitals between 1996 and 2002. We used electronic medical records to concatenate hospital, emergency department and outpatient health care encounters for bronchiolitis into discrete episodes of care. We used descriptive statistics to report frequency and duration of bronchiolitis episodes and used logistic regression to assess the effect of gestational age and other clinical and demographic predictors on the outcome of bronchiolitis episodes.

Results

Among all infants, the rate of bronchiolitis episodes was 162 per 1000 children during the first 2 years of life; approximately 40% required >1 day of medical attention with a mean duration of 7.0 ± 5.9 days. Prematurity was associated with increased risk of bronchiolitis episodes and longer duration. Bronchiolitis episodes rates per 1000 infants were 246 for 32–33 weeks gestational age, 204 for 34–36 weeks, and 148–178 for >36 weeks. Male gender, African-American and Hispanic race/ethnicity, and parental history of asthma were associated with an increased risk of having a bronchiolitis episode and/or longer duration.

Conclusions

Bronchiolitis episodes of care are frequent during the first two years of life and the duration ranges from 1 to 27 days. Prematurity was associated with more frequent and longer duration of bronchiolitis episodes of care, which may reflect illness severity and/or perceived vulnerability.