Table 3

Multivariate predictors of RED events (derivation cohort, N= 23,127)
Variables Odds Ratio (95% CI) P Value
Demographics/Laboratory/Vital Signs
Age >54 years 1.59 (1.24 - 2.04) <0.001
SpO2 (%) (min) ≤86 1.73 (1.04 - 2.88) 0.03
Diastolic BP (mm Hg) (max) >120 3.17 (1.16 - 8.66) 0.03
AST (U/L) (min) >250 2.89 (1.62 - 5.17) <0.001
pCO2 (mm Hg) (max) ≤22 3.72 (1.64 - 8.40) 0.002
pCO2 (mm Hg) (max) >70 4.61 (1.84 - 11.56) 0.001
WBC (103 cells/mm3) (min) >11 1.36 (1.03 - 1.79) 0.03
Platelets (103 cells/mm3) (min) <100 1.76 (1.18 - 2.64) 0.01
Potassium (mEq/dL) (max) >5.1 1.77 (1.22 - 2.56) 0.003
Orders
Arterial Blood Gas 2.08 (1.52 - 2.85) <0.001
Electrocardiogram 2.05 (1.54 - 2.73) <0.001
Stat Physician Order a 2.20 (1.53 - 3.16) <0.001
Summary Variable
High Risk Floor Assignment b 5.71 (4.34 - 7.51) <0.001
MEWS c 1.36 (1.28 - 1.44) <0.001
Derivation: 0.87 (0.85 - 0.89) - 298 events
Validation: 0.85 (0.82 - 0.87) - 287 events

a Stat orders for head magnetic resonance imaging or computed tomography scan, chest plain film x-rays or computed tomography scan, and abdominal ultrasonography; b includes floors that comprise the top 15% of events; c elements consists of systolic blood pressure, heart rate, respiratory rate, temperature, and level of consciousness.

Alvarez et al.

Alvarez et al. BMC Medical Informatics and Decision Making 2013 13:28   doi:10.1186/1472-6947-13-28

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