## Figure 1.
Correlation of total, adjusted, and free phenytoin plasma concentrations. (A) Correlation of PHT_{free }versus PHT_{total/10 }for 756 patients is shown. For patients who had multiple phenytoin measurements, only
the chronologically first set of PHT_{free }and PHT_{total/10 }measurements is plotted. The solid line is the line of identity, and the dashed line
is from linear regression: PHT_{free }= 0.385 + 1.104 * PHT_{total/10 }(R^{2 }= 0.51). The 95% confidence intervals of the intercept is (0.355, 0.415) and for the
slope is (1.045,1.163). (B) Correlation of PHT_{free }versus PHT_{adj_free }is shown using same source of patient data as in (A). The dashed line is from linear regression: PHT_{free }= 0.223 + 0.980 * PHT_{adj_free }(R^{2 }= 0.62). The 95% confidence intervals of the intercept is (0.129, 0.317) and for the
slope is (0.926, 1.034)
Krasowski and Penrod |