Table 3

Pharmacokinetic geometric mean ratios of AVI-014/filgrastim at 4 μg/kg

PK parameter

Dose mcg/kg

Geo Mean AVI-014 (n = 16)

Geo Mean Filgrastin (n = 8)

P value

Geo Mean Ratio (90% CI)


AUC(0–72)

4

169.545

170,259

0.9766

1.00 (0.76, 1.31)


Cmax

4

18,830

21,855

0.2952

0.86 (0.66, 1.13)


Varki et al. BMC Clinical Pharmacology 2009 9:2   doi:10.1186/1472-6904-9-2

Open Data