Table 9

Regression analysis of initial glutathione and change in glutathione (from before and after phase 1).

Adjusted R2

P-Value

Equation

Most Significant variables


Glutathione (n = 59)

0.25

0.003

378.7-48.8 PbB + 3.67AsB -219 CdB +2.49 Sn9 +369 TlB -69.9 Hg9 -4.32 As9 +598 Cd9

Cd9**, PbB*, Sn9*, Tl9*, As9*

Change in glutathione (n = 37)

0.29

0.002

104-2.26Sn9+87.8Hg9-669Cd9

Cd**


The analysis involved metals at Baseline (B) and after the 9th dose (9).

Adams et al. BMC Clinical Pharmacology 2009 9:16   doi:10.1186/1472-6904-9-16

Open Data