Table 4

Annual number of HES finished consultant episodes with an 'external code' for an adverse drug reaction

ICD-10

1998–9
1999–00
2000–1
2001–2
2002–3
2003–4
2004–5
% Change 1998–2005

Y40
Systemic antibiotics
4,206
4,212
4,533
4,341
4,697
5,624
6,449
53.3
Y41
Other systemic anti-infectives/anti-parasitics
829
816
1,017
945
1,195
1,134
1,453
75.3
Y42
Hormones (including synthetic, antagonists)
4,547
5,088
4,934
5,113
5,803
5,461
5,319
17
Y43
Primarily systemic agents
7,501
8,271
9,078
9,877
10,766
11,226
12,054
60.7
Y44
Agents primarily affecting blood constituents
4,062
4,483
4,723
4,797
5,230
5,995
4,272
5.2
Y45
Analgesics/antipyretics/anti-inflammatory
5,951
6,726
6,787
6,819
7,540
8,079
9,004
51.3
Y46
Antiepileptics/antiParkinsonism drugs
1,230
1,267
1,224
1,340
1,401
1,501
1,628
32.4
Y47
Sedatives, hypnotics, anti-anxiety drugs
370
400
450
430
480
586
560
51.4
Y48
Anaesthetics, therapeutic gases
414
538
502
440
505
521
531
28.3
Y49
Psychotropic drugs
1,653
1,678
2,008
1,992
1,953
2,364
2,544
53.9
Y50
Central nervous system stimulants
46
67
75
76
69
71
93
102.2
Y51
Drugs affecting autonomic nervous system
1,702
2,056
2,277
2,470
2,686
3,239
3,532
107.5
Y52
Agents primarily affecting cardiovascular system
4,044
4,752
5,376
5,667
6,234
6,836
7,768
92.1
Y53
Agents primarily affecting gastrointestinal system
398
410
486
416
461
579
656
64.8
Y54
Agents affecting water/mineral balance/uric acid
2,136
2,617
2,945
3,526
4,151
5,118
5,638
164
Y55
Agents affecting muscle/respiratory system
312
299
342
321
323
430
422
35.3
Y56
Topical agents affecting skin/ENT, dental
1,138
1,236
983
1,202
1,065
1,079
1,224
7.6
Y57
Other and unspecified medicaments
1,524
1,715
1,780
1,907
1,906
2,014
2,398
57.3
Y58
Bacterial vaccines
226
347
255
182
197
356
281
24.3
Y59
Other vaccines/biologicals
266
407
338
299
281
405
470
76.7

Total

42,555
47,385
50,113
52,160
56,943
62,618
66,296
55.8

Patel et al. BMC Clinical Pharmacology 2007 7:9   doi:10.1186/1472-6904-7-9