Table 3

Annual number of Hospital Episode Statistics finished consultant episodes with a primary diagnosis for an ADR (ICD-10 code)

ICD-10

1998–9
1999–00
2000–1
2001–2
2002–3
2003–4
2004–5
% Change 1998–2005

D59.0/2
Drug induced haemolytic anaemia
15
30
28
37
34
36
154
926.7
D61.1
Drug induced aplastic anaemia
101
116
114
186
182
162
241
138.6
E03.2
Hypothyroidism due to medicaments
23
23
12
12
19
13
26
13.0
E27.3
Drug induced adrenocortical failure
24
22
24
38
39
53
59
145.8
F11
Mental disorders due to opioids
4360
4287
4398
4187
3916
3690
3746
-14.1
F13
Mental disorders due to sedatives/hypnotics
223
247
247
239
232
206
189
-15.2
F19
Mental disorders due to multiple psychoactive drugs
3513
3137
2725
2643
2601
2690
2775
-21.0
G21.0
Malignant neuroleptic syndrome
101
106
121
108
102
93
128
26.7
G21.1
Drug induced Parkinsonism
145
115
124
133
112
108
149
2.8
G24.0
Drug induced dystonia
149
130
145
130
115
152
109
-26.8
G25.1/4/6
Drug induced extrapyramidal syndrome/chorea/tics
136
146
110
125
44
51
48
-64.7
G72.0
Drug induced myopathy
47
53
51
51
57
39
55
17.0
H91.0
Ototoxic hearing loss
2
5
3
3
2
U/C1
U/C
U/C
I42.7
Drug induced cardiomyopathy
25
25
53
38
67
77
61
144.0
J70.2/3/4
Drug induced interstitial lung disorders
54
45
43
43
86
71
94
74.1
K71
Drug induced liver disease
406
318
372
351
459
437
448
10.3
L56.0/1
Drug induced phototoxicity
4
5
2
4
1
3
5
25.0
M10.2
Drug induced gout
30
27
13
24
22
22
34
13.3
M32.0
Drug induced systemic lupus erythematosus
17
20
12
13
14
10
26
52.9
M34.2
Drug induced systemic sclerosis
3
3
4
3
U/C
U/C
U/C
U/C
N14
Drug induced nephropathy
60
69
92
85
100
318
414
590.0
T88.3
Malignant hyperthermia due to anaesthesia
6
4
10
3
3
5
4
-33.3
T88.6
Drug induced anaphylaxis
366
435
399
384
375
469
563
53.8
T88.7
Unspecified adverse drug effect
696
737
721
602
664
748
1068
53.4

Total

10506
10105
9823
9442
9246
9453
10396
-1.0

1U/C – unclassified: data not available due to a coding change

Patel et al. BMC Clinical Pharmacology 2007 7:9   doi:10.1186/1472-6904-7-9