Figure 14.

Semi log plots of long time cannabinol washout for the simple one well mixed compartment model (green) and the PBPK N = 1 (red) and N = 3 (black) adipose models. Plots are shown for liver cannabinol clearance (Cl) varying from 1.0 l/min (the optimal value for cannabinol) down to 0.01 l/min. The inset shows the early time result for the 0.01 l/min clearance.