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Resolution: standard / high Figure 9.
Comparison of PBPK linear (left) or semi-log (right) plots of model predictions and
experimental data for cefatrizine from Pfeffer et. al. [31]. The top row is for the flow limited model (fclear = 1) with an average error between
PBPK model and experimental data of 5.4%. The addition of a small capillary permeability
limitation does not significantly improve the fit (not shown).
Levitt BMC Clinical Pharmacology 2003 3:3 doi:10.1186/1472-6904-3-3 |