The decision represented by the node (square) at the left, is between receiving antidote, NAC and methionine when a patients is presented for treatment within 10 hours (a) and 10-24 hours (b) of the acute ingestion of paracetamol. Each chance event is shown as a solid circle and represent either the chance of developing liver failure (ALT > 1000 IU) or not developing liver failure. The numbers on each branch are probabilities and outcome is represented by cost [in million (M) rupees (LKR)] per number of lives saves (1000 hypothetical patients in each arm were considered) at the terminal node (rectangular). The probabilities and outcomes are explained in Table 1.
Senarathna et al. BMC Clinical Pharmacology 2012 12:6 doi:10.1186/1472-6904-12-6