Table 3 

Distribution of the observed concentrations of panitumumab relative to the 90% predictive interval 

Distribution in Relation to 90% Prediction Interval 
AntibodyPositive Patients 
AntibodyNegative Patients 
Pvalue^{†} 




N 
% 
95% CI 
Pvalue* 
N 
% 
95% CI 
Pvalue* 



Below 
2 
5.3 
0.6 17.8 
0.07 
3 
4.4 
0.9  12.4 
0.13 
0.88 
Above 
5 
13.2 
4.4  28.1 
7 
10.3 
4.2  20.1 

Within 
31 
81.6 
65.7  92.3 
58 
85.3 
74.6  92.7 



*Chisquare test with hypothesized proportions (5% below, 5% above, 90% within). ^{†}Chisquare test of antibodypositive proportion vs antibodynegative proportion. 

Weeraratne et al. BMC Clinical Pharmacology 2011 11:17 doi:10.1186/147269041117 