Open Access Highly Accessed Research article

Knowledge and adherence to antiretroviral therapy among adult people living with HIV/AIDS treated in the health care centers of the association "Espoir Vie Togo" in Togo, West Africa

Yao Potchoo1*, Kpatcha Tchamdja2, Agnon Balogou1, Vincent P Pitche1, Innocent P Guissou3 and Etienne K Kassang4

Author Affiliations

1 Université de Lomé, Faculté Mixte de Médecine et de Pharmacie, BP 1515, Lomé - Togo

2 Centre Hospitalier Universitaire de Kara, Service de Pharmacie BP 18 - Kara - Togo

3 Université de Ouagadougou - UFR/SDS 03 BP 7021 Ouagadougou 03 - Burkina Faso

4 Espoir Vie Togo, Région Centrale (EVT/RC) - Togo

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BMC Clinical Pharmacology 2010, 10:11  doi:10.1186/1472-6904-10-11

Published: 17 September 2010

Abstract

Background

The efficiency of antiretroviral therapy (ART) depends on a near perfect level of patients' adherence. The level of adherence of adults HIV-infected patients treated in the HIV/AIDS health care centres of the association "Espoir Vie Togo" in Togo, West Africa is not properly documented. The aim of the present study was to examine by means of self-reports the knowledge, the adherence level and associated factors to antiretroviral therapy (ART) among these patients.

Methods

We conducted a cross-sectional survey among adult people living with HIV/AIDS (PLWHA) through a structured questionnaire.

Results

A total of 99 patients were enrolled. Among them, 55.6% knew the name of antiretroviral agents of regimens prescribed. All patients had a good knowledge of treatment schedule. The treatment regimens based on 2 NRTIs + 1 NNRTI were used in 90% of patients. The average adherence rate was 89.8% of the total doses prescribed while 62.62% of patients showed an adherence rate of 95% or above. The treated groups were similar in term of median % of medication doses taken according to PLWHA epidemiological characteristics. However, patients reported forgetting (34.9%), travel (25.6%), cost of treatment (13.9%) and side effects (11.6%) as the main factors of missing at least once a dose intake.

Conclusion

These results should encourage the association and all the involved actors in the HIV/AIDS's program to strengthen counseling, education and information interventions for HIV-infected patients in order to overcome the potential barriers of poor adherence.