Trauma-induced increase of caspase-8 activity in IVD cells. Analysis of the initiating caspase-8 within the extrinsic receptor-mediated apoptosis pathway revealed a significant increase compared to non-traumatic control IVD. * p < 0.05 as determined by Student's t test (trauma vs. control).
Heyde et al. BMC Clinical Pathology 2006 6:5 doi:10.1186/1472-6890-6-5