Table 3 |
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|
Summary of LOH data in 63 gliomas. |
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|
Deletion detected |
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|
|
||||||||
|
Group |
Age |
Sex |
Chromosome 1 |
Chromosome 19 |
Histological Diagnosis: |
WHO Grade |
||
|
|
||||||||
|
D1S508 |
D1S2734 |
D19S219 |
D19S412 |
|||||
|
|
||||||||
|
1 |
53 |
F |
1 deletion |
non-informative |
0 deletion |
non-informative |
oligodendroglioma, anaplastic |
3 |
|
34 |
F |
1 deletion |
1 deletion |
1 deletion |
1 deletion |
oligodendroglioma, anaplastic |
3 |
|
|
28 |
F |
non-informative |
0 deletion |
0 deletion |
0 deletion |
oligodendroglioma, anaplastic |
3 |
|
|
27 |
M |
0 deletion |
non-informative |
1 deletion |
1 deletion |
oligodendroglioma, anaplastic |
3 |
|
|
* |
16 |
M |
0 deletion |
0 deletion |
0 deletion |
non-informative |
oligodendroglioma, anaplastic |
3 |
|
48 |
M |
non-informative |
1 deletion |
1 deletion |
1 deletion |
oligodendroglioma, anaplastic |
3 |
|
|
45 |
M |
0 deletion |
0 deletion |
1 deletion |
1 deletion |
oligodendroglioma, anaplastic |
3 |
|
|
41 |
M |
non-informative |
1 deletion |
1 deletion |
1 deletion |
oligodendroglioma, anaplastic |
3 |
|
|
30 |
M |
non-informative |
1 deletion |
1 deletion |
non-informative |
oligodendroglioma, anaplastic |
3 |
|
|
57 |
F |
non-informative |
non-informative |
1 deletion |
1 deletion |
oligodendroglioma |
2 |
|
|
56 |
M |
1 deletion |
1 deletion |
1 deletion |
non-informative |
oligodendroglioma |
2 |
|
|
54 |
F |
1 deletion |
1 deletion |
1 deletion |
1 deletion |
oligodendroglioma |
2 |
|
|
53 |
F |
1 deletion |
1 deletion |
1 deletion |
1 deletion |
oligodendroglioma |
2 |
|
|
52 |
M |
1 deletion |
1 deletion |
non-informative |
1 deletion |
oligodendroglioma |
2 |
|
|
49 |
M |
1 deletion |
1 deletion |
1 deletion |
1 deletion |
oligodendroglioma |
2 |
|
|
43 |
F |
1 deletion |
1 deletion |
1 deletion |
non-informative |
oligodendroglioma |
2 |
|
|
38 |
F |
non-informative |
0 deletion |
non-informative |
0 deletion |
oligodendroglioma |
2 |
|
|
37 |
M |
1 deletion |
1 deletion |
non-informative |
1 deletion |
oligodendroglioma |
2 |
|
|
37 |
M |
0 deletion |
0 deletion |
0 deletion |
0 deletion |
oligodendroglioma |
2 |
|
|
35 |
M |
1 deletion |
1 deletion |
1 deletion |
1 deletion |
oligodendroglioma |
2 |
|
|
32 |
M |
non-informative |
non-informative |
0 deletion |
non-informative |
oligodendroglioma |
2 |
|
|
28 |
M |
non-informative |
0 deletion |
non-informative |
0 deletion |
oligodendroglioma |
2 |
|
|
25 |
M |
1 deletion |
non-informative |
1 deletion |
1 deletion |
oligodendroglioma |
2 |
|
|
* |
17 |
M |
0 deletion |
0 deletion |
non-informative |
0 deletion |
oligodendroglioma |
2 |
|
* |
2 |
F |
0 deletion |
0 deletion |
0 deletion |
0 deletion |
oligodendroglioma |
2 |
|
#,+ |
41 |
F |
1 deletion |
0 deletion |
1 deletion |
0 deletion |
oligoastrocytoma, anaplastic |
3 |
|
54 |
M |
0 deletion |
0 deletion |
0 deletion |
0 deletion |
oligoastrocytoma, anaplastic |
3 |
|
|
37 |
F |
0 deletion |
0 deletion |
1 deletion |
1 deletion |
oligoastrocytoma, anaplastic |
3 |
|
|
34 |
M |
0 deletion |
0 deletion |
0 deletion |
0 deletion |
oligoastrocytoma, anaplastic |
3 |
|
|
48 |
M |
0 deletion |
0 deletion |
0 deletion |
0 deletion |
oligoastrocytoma |
2 |
|
|
48 |
F |
0 deletion |
0 deletion |
0 deletion |
0 deletion |
oligoastrocytoma |
2 |
|
|
26 |
M |
1 deletion |
non-informative |
1 deletion |
1 deletion |
oligoastrocytoma |
2 |
|
|
59 |
F |
1 deletion |
non-informative |
0 deletion |
0 deletion |
glioblastoma multiforme |
4 |
|
|
58 |
F |
0 deletion |
0 deletion |
1 deletion |
1 deletion |
glioblastoma multiforme |
4 |
|
|
57 |
F |
non-informative |
0 deletion |
0 deletion |
non-informative |
glioblastoma multiforme |
4 |
|
|
53 |
M |
0 deletion |
0 deletion |
1 deletion |
1 deletion |
glioblastoma multiforme |
4 |
|
|
46 |
F |
0 deletion |
0 deletion |
0 deletion |
0 deletion |
glioblastoma multiforme |
4 |
|
|
31 |
F |
1 deletion |
1 deletion |
1 deletion |
1 deletion |
glioblastoma multiforme |
4 |
|
|
29 |
M |
0 deletion |
0 deletion |
0 deletion |
non-informative |
glioblastoma multiforme |
4 |
|
|
* |
8 |
M |
1 deletion |
1 deletion |
1 deletion |
1 deletion |
glioblastoma multiforme |
4 |
|
* |
2 |
M |
non-informative |
0 deletion |
0 deletion |
non-informative |
glioblastoma multiforme |
4 |
|
|
||||||||
|
2 |
62 |
M |
0 deletion |
0 deletion |
non-informative |
1 deletion |
oligodendroglioma, anaplastic |
3 |
|
70 |
M |
non-informative |
0 deletion |
0 deletion |
non-informative |
oligodendroglioma, anaplastic |
3 |
|
|
71 |
F |
non-informative |
0 deletion |
0 deletion |
non-informative |
oligodendroglioma, anaplastic |
3 |
|
|
66 |
M |
non-informative |
0 deletion |
0 deletion |
non-informative |
oligodendroglioma, anaplastic |
3 |
|
|
74 |
F |
non-informative |
non-informative |
0 deletion |
0 deletion |
oligodendroglioma, anaplastic |
3 |
|
|
62 |
M |
0 deletion |
0 deletion |
0 deletion |
non-informative |
oligodendroglioma |
2 |
|
|
61 |
M |
0 deletion |
0 deletion |
non-informative |
0 deletion |
oligoastrocytoma, anaplastic |
3 |
|
|
78 |
M |
0 deletion |
0 deletion |
0 deletion |
0 deletion |
oligoastrocytoma, anaplastic |
3 |
|
|
60 |
M |
non-informative |
0 deletion |
1 deletion |
1 deletion |
glioblastoma multiforme |
4 |
|
|
61 |
M |
0 deletion |
0 deletion |
non-informative |
0 deletion |
glioblastoma multiforme |
4 |
|
|
64 |
M |
0 deletion |
non-informative |
0 deletion |
0 deletion |
glioblastoma multiforme |
4 |
|
|
64 |
M |
0 deletion |
0 deletion |
0 deletion |
0 deletion |
glioblastoma multiforme |
4 |
|
|
# |
65 |
F |
1 deletion |
0 deletion |
1 deletion |
non-informative |
glioblastoma multiforme |
4 |
|
66 |
M |
1 deletion |
1 deletion |
1 deletion |
1 deletion |
glioblastoma multiforme |
4 |
|
|
66 |
M |
non-informative |
0 deletion |
non-informative |
0 deletion |
glioblastoma multiforme |
4 |
|
|
70 |
M |
0 deletion |
0 deletion |
1 deletion |
1 deletion |
glioblastoma multiforme |
4 |
|
|
74 |
M |
0 deletion |
0 deletion |
0 deletion |
0 deletion |
glioblastoma multiforme |
4 |
|
|
74 |
M |
non-informative |
0 deletion |
non-informative |
non-informative |
glioblastoma multiforme |
4 |
|
|
75 |
M |
0 deletion |
0 deletion |
1 deletion |
1 deletion |
glioblastoma multiforme |
4 |
|
|
76 |
M |
1 deletion |
non-informative |
0 deletion |
0 deletion |
glioblastoma multiforme |
4 |
|
|
70 |
M |
0 deletion |
0 deletion |
0 deletion |
0 deletion |
dysembryoplastic neuroepithial tumor |
1 |
|
|
73 |
F |
0 deletion |
0 deletion |
0 deletion |
0 deletion |
astrocytoma, anaplastic |
3 |
|
|
|
||||||||
|
* pediatric patients. # partial deletions on chromosome 1. + anaplastic with post radiation changes. Homozygous: Both parental alleles in the patient's normal constitutional DNA are identical and migrated as 1 apparent band on a polyacrylamide gel. Homozygous alleles were considered non-informative and not used in the analysis. 0 deletion: The parental alleles migrated as 2 separate bands (heterozygous alleles) and no LOH was detected in the tumor DNA. 1 deletion: The tumor DNA demonstrated a LOH at that locus. |
||||||||
|
Myal et al. BMC Clinical Pathology 2003 3:6 doi:10.1186/1472-6890-3-6 |
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