Table 2

Clinical and immunopathological parameters of patients infected with Uganda genotype and those infected by non-Uganda genotypes of M. tuberculosis
Patient characteristics Uganda/Non-Uganda n (%) Crude Adjusted*
OR (95% CI) P-value OR (95% CI) P-value
Clinical presentations
 Fever less than 6 months 39 (70%)/44 (69%) 1.0 (0.5-2.3) 0.916 1.1 (0.5-2.5) 0.870
 Night sweats 43 (77%)/55 (86%) 0.5 (0.2-1.4) 0.200 0.5 (0.2-1.4) 0.213
 Cough 27 (48%)/30 (46%) 1.1 (0.5-2.2) 0.821 1.4 (0.7-3.1) 0.435
Radiological Presentations
 Abnormal Chest X-ray 20 (43%)/27 (47%) 0.8 (0.4-1.8) 0.624 0.8 (0.4-1.9) 0.644
 Abdominal lymphadenopathy 21 (38%)/39 (60%) 0.4 (0.2-0.8) 0.014 0.5 (0.2-1.0) 0.046
Lymph node Pathology
 Single site lymphadenitis 34 (62%)/32 (50%) 1.6 (0.8-3.4) 0.197 1.4 (0.6-2.9) 0.435
 Generalized lymphadenopathy 5 (9%)/11 (17%) 0.5 (0.2-1.5) 0.204 0.7 (0.2-2.1) 0.474
 Lymph node ≥ 4 cm 15 (28%)/28 (45%) 0.5 (0.2-1.0) 0.055 0.6 (0.3-1.3) 0.157
 Necrosis 52 (93%)/61 (94%) 0.9 (0.2-3.6) 0.827 0.8 (0.2-3.4) 0.741
 Giant cells 28 (50%)/25 (38%) 1.6 (0.8-3.3) 0.203 1.3 (0.6-2.8) 0.569
 Macrophages 53 (95%)/58 (89%) 2.1 (0.5-8.7) 0.290 1.5 (0.4-6.9) 0.577
 Granulomas 47 (84%)/46 (71%) 2.2 (0.9-5.3) 0.091 1.9 (0.8-4.8) 0.196
 Ziehl Neelsen positive smear 29 (52%)/42 (65%) 0.6 (0.3-1.2) 0.152 0.7 (0.3-1.5) 0.348

Adjusted* = Adjusted for Age, Sex and HIV status; OR = Odds ratio, Cl = Confidence Interval.

Logistic regression.

Wamala et al.

Wamala et al. BMC Clinical Pathology 2014 14:14   doi:10.1186/1472-6890-14-14

Open Data