Table 2

Associations of the HDAC-1, -2 and 3 and Ki-67 with pathologic characteristics (n = 174)
Variable Categorization HDAC-1 expression HDAC-2 expression HDAC-3 expression Ki-67 expression
Low High p Low High p Low High p Low High p
Tumor stage (WHO 1973)a
pTa 59 31 0.162 55 35 0.811 37 53 0.257 71 19 <0.001
pT1 37 31 37 31 30 38 35 33
pT2 5 8 7 6 2 11 2 11
pT3 2 0 1 1 1 1 0 2
pT4 1 0 1 0 1 0 0 1
Histologic grade (WHO 1973)a
G1 29 15 0.022 32 12 0.026 20 24 0.425 39 5 <0.001
G2 57 30 50 37 37 50 61 26
G3 18 25 19 24 14 29 8 35
Histologic grade (WHO 2004)b
Low grade 71 30 0.001 68 33 0.005 49 52 0.019 87 14 <0.001
High grade 33 40 33 40 22 51 21 52
Adjacent carcinoma in situb
No 96 62 0.432 96 62 0.032 65 93 1.00 105 53 <0.001
Yes 8 8 5 11 6 10 3 13
Multiplicityb
Solitary 79 45 0.124 77 47 0.093 49 75 0.587 86 38 0.003
Multifocal 25 25 24 26 22 28 22 28
Growth patternb
Papillary 97 62 0.278 94 65 0.416 65 94 1.00 107 52 <0.001
Solid 7 8 7 8 6 9 1 14

aChi-Square Pearson (2-sided); bold face representing p-values < 0.05.

bFisher’s exact test (2-sided); bold face representing p-values < 0.05.

Poyet et al.

Poyet et al. BMC Clinical Pathology 2014 14:10   doi:10.1186/1472-6890-14-10

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