Table 7

Results of Cox regression analysis summarizing prognostic factors in patients with soft tissue sarcomas
All patients, N = 193 Men, N = 81 Women, N = 112
Factor Hazard ratio 95% CI P Hazard ratio 95% CI P Hazard ratio 95% CI P
Age
0–59 years 1.00 1.00 1.00
≥60 years 1.84 1.15-2.95 0.012 1.69 0.65-4.41 0.282 1.51 0.83-2.77 0.179
Nationality
Norwegian 1.00 1.00 1.00
Russian 1.49 0.88-2.52 0.143 1.39 0.41-4.66 0.598 2.51 1.20-5.21 0.014
Tumor size
<5 cm 1.00 0.138* 1.00 0.668* 1.00 0.020*
5–9 cm 1.47 0.79-2.73 0.226 1.68 0.54-5.25 0.372 1.71 0.77-3.77 0.187
≥10 cm 1.91 1.01-3.60 0.047 1.32 0.40-4.39 0.652 3.14 1.38-7.15 0.006
Malignancy grade FNCLCC
1 1.00 <0.001* 1.00 <0.001 1.00 0.004*
2 2.72 1.36-5.46 0.005 3.07 0.86-10.96 0.084 4.33 1.76-10.67 0.001
3 4.61 2.26-9.40 <0.001 15.47 4.36-54.97 <0.001 4.23 1.64-10.89 0.003
Resection margins
Wide 1.00 1.00 1.00
Non-wide 1.87 1.16-3.02 0.010 7.69 2.67-22.16 <0.001 0.81 0.42-1.54 0.512
Skp2
Low 1.00 1.00 1.00
High 1.48 0.87-2.52 0.151 0.46 0.19-1.12 0.088 2.52 1.31-4.85 0.006
ER / PGR
Low/low 1.00 0.006* 1.00 0.004* 1.00 0.216*
Low/high 2.64 1.43-4.85 0.002 4.99 1.31-18.97 0.018 1.91 0.89-4.11 0.097
High/low 2.07 1.15-3.73 0.015 8.35 2.55-27.36 <0.001 1.76 0.79-3.93 0.170
High/high 1.16 0.57-2.38 0.682 4.50 0.96-21.13 0.056 0.92 0.36-2.35 0.868

* Overall significance as a prognostic factor. The difference between the individual p-value and total p-value in the multivariate analysis is relevant in cases where there are more than two categories for a given variable. Overall p-value is calculated based on a general assessment of all categories for the given variable, but the individual p-value only calculates the significance of a given category versus the reference category.

Sorbye et al.

Sorbye et al. BMC Clinical Pathology 2013 13:9   doi:10.1186/1472-6890-13-9

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