Table 2

Frequency of PGC, MUC1 and MUC2 protein expression in gastric diseases
Staining score SG AG GC GC(n = 70)
HMDA PDA MA or SRCC
n = 57 n = 57 n = 70 n = 28 n = 30 n = 12
PGC
2.0-3.0 19(33.3) 2(3.5) 0(0.0) 0(0.0) 0(0.0) 0(0.0)
1.0-1.9 29(50.9) 14(24.6) 0(0.0) 0(0.0) 0(0.0) 0(0.0)
0.1-0.9 9(15.8) 13(22.8) 0(0.0) 0(0.0) 0(0.0) 0(0.0)
0 0(0.0) 28(49.1) 70(100.0) 28(100.0) 30(100.0) 12(100.0)
P1 <0.0001 <0.0001 -
P2 1.000 1.000 -
MUC1
2.0-3.0 24(42.1) 29(50.9) 21(30.4) 12(42.9) 9(31.0) 0(0.0)
1.0-1.9 19(33.3) 19(33.3) 15(21.7) 8(28.6) 6(20.7) 1(8.3)
0.1-0.9 13(22.8) 9(15.8) 23(33.3) 7(25.0) 12(41.4) 4(33.0)
0 1(1.8) 0(0.0) 10(14.5) 1(3.6) 2(6.9) 7(58.3)
P3 0.012 0.0003 -
P4 <0.0001 0.0004 -
MUC2
2.0-3.0 2(3.5) 46(80.7) 12(17.1) 6(21.4) 2(6.7) 4(33.3)
1.0-1.9 0(0.0) 6(10.5) 8(11.4) 3(10.7) 2(6.7) 3(25.0)
0.1-0.9 0(0.0) 3(5.3) 19(27.1) 9(32.1) 8(26.7) 2(16.7)
0 55(96.5) 2(3.5) 31(44.3) 10(35.7) 18(60.0) 3(25.0)
P5 <0.0001 <0.0001 -
P6 0.273 0.013 -
P7 <0.0001 <0.0001 -
P8 <0.0001 <0.0001 -
P9 <0.0001 0.001 -

Note: Statistical analysis used nonparametric tests and Fisher’s exact tests. P1, P3, P5 means the significance compared with GC group, respectively. P2, P4, P6 means the significance compared with MA or SRCC group, respectively. P7 means the significance compared with HMDA group; P8 means the significance compared with PDA group; P9 means the significance compared with MA or SRCC group.

Xu et al.

Xu et al. BMC Clinical Pathology 2013 13:21   doi:10.1186/1472-6890-13-21

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