Table 5 

Mean HER2/CEN17 ratio and signal numbers for all specimens. 

Mean 
N 
Std. Deviation 



HER2/CEN17 ratio 
HER2 CISH 
1.64 
352 
1.21 
HER2 FISH 
1.78^{a} 
358 
1.90 

PathVysion 
1.77^{b} 
361 
1.83 

HER2 signals 
HER2 CISH 
74.44 
352 
65.65 
HER2 FISH 
75.58^{c} 
358 
92.92 

PathVysion 
71.76^{d} 
361 
76.88 

CEN17 signals 
HER2 CISH 
43.89 
352 
11.98 
HER2 FISH 
41.20^{e} 
358 
13.09 

PathVysion 
41.01^{f} 
361 
21.88 



Signal copy numbers were normalized to 20 nuclei a) Significant different from CISH ratio in a two tailed, paired ttest (N = 348, P < 0.001) b) Significant different from CISH ratio in a two tailed, paired ttest (N = 350, P = 0.001) c) Not significant different from CISH HER2 signals in a two tailed, paired ttest (N = 348, P = 0.245) d) Not significant different from CISH HER2 signals in a twotailed, paired ttest (N = 350, P = 0.284) e) Significant different from CISH CEN17 signals in a two tailed, paired ttest (N = 348, P < 0.001) f) Significant different from CISH CEN17 signals in a twotailed, paired ttest (N = 350, P < 0.003) 

Mollerup et al. BMC Clinical Pathology 2012 12:3 doi:10.1186/14726890123 