Table 4

Cross tabulation of HER2 gene status for CISH versus PathVysion FISH.

PathVysion HER-2 FISH


Non-amplified

Amplified

Total


HER2 CISH pharmDx™

Non-amplified

302

4

306

Amplified

4

40

44

Total

306

44

350


Two tailed 95% confidence intervals are based on the binomial distribution. Overall agreement: (342/350 × 100) = 97.7% (CI95: 95.7%; 98.9%), Positive agreement: (40/44 × 100) = 90.9% (CI95: 79.8%; 96.9%), Negative agreement: (302/306 × 100) = 98.7% (CI95: 96.9%; 99.6%) and Kappa: 0.90 (SE: 0.04)

Mollerup et al. BMC Clinical Pathology 2012 12:3   doi:10.1186/1472-6890-12-3

Open Data