Qualitiy of cell free serum DNA. (A) reflects the amplification success for each sample using MBD or silica membrane based serum DNA. A maximum of 12 fragments per sample was possible and in sum 34 samples per isolation approach were analyzed. (B) shows the amplification success of each fragment getting amplified across all analyzed samples. Both plots (A, B) are based on the analysis of two multiplex PCRs performed on serum or plasma DNA isolates (source 1, 2).
Wielscher et al. BMC Clinical Pathology 2011 11:11 doi:10.1186/1472-6890-11-11