Table 1

Functional groups of frankincense oil-regulated genes in bladder cancer J82 cells

Function

Gene Symbol

Description


Cytokines

CCL2

chemokine (C-C motif) ligand 2

CCL5

chemokine (C-C motif) ligand 5

CMTM8

CKLF-like MARVEL transmembrane domain containing 8

CXCL2

chemokine (C-X-C motif) ligand 2

IL1A

interleukin 1, alpha

IL6

interleukin 6 (interferon, beta 2)

IL8

interleukin 8

Enzymes – kinases

ABL2

v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)

AXL

AXL receptor tyrosine kinase

CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

CLK1

CDC-like kinase 1

DLG1

discs, large homolog 1 (Drosophila)

FGFR1

fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)

PSTK

phosphoseryl-tRNA kinase

SGK1

serum/glucocorticoid regulated kinase 1

SNF1LK

SNF1-like kinase

TAOK1

TAO kinase 1

TRIB1

tribbles homolog 1 (Drosophila)

Enzymes – peptidases

RCE1

RCE1 homolog, prenyl protein peptidase (S. cerevisiae)

Enzymes – phosphatases

DUSP10

dual specificity phosphatase 10

DUSP2

dual specificity phosphatase 2

DUSP5

dual specificity phosphatase 5

MTMR6

myotubularin related protein 6

NUDT2

nudix (nucleoside diphosphate linked moiety X)-type motif 2

PPP3R1

protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform

PTPN23

protein tyrosine phosphatase, non-receptor type 23

Membrane Receptors

PLAUR

plasminogen activator, urokinase receptor

PLXNA1

plexin A1

PLXNA3

plexin A3

SSTR1

somatostatin receptor 1


Frank et al. BMC Complementary and Alternative Medicine 2009 9:6   doi:10.1186/1472-6882-9-6

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