Figure 5.

Perna treatment ameliorated established CIA. After CIA induction, mice were randomly assigned to Perna (red dotted line), DMG (black dashed line) or control (blue solid line) groups and scored twice daily for 107 days. Scoring was based on the following criteria: 0, no pathology; 1, swelling in one limb; 2, moderate swelling in multiple limbs with joint locking; and 3, pronounced swelling in all four limbs with joint locking.