|
Combinatory effect of MAK-4 and MAK-5 on H-ras-induced transformation assessed by focus formation assay |
||||
| Treatment |
Exogenous H-ras gene |
Cytoxicity (% survival) |
Foci/plate ± SD |
Relative number of foci |
|
|
||||
| Mock control |
- |
100 |
0 |
- |
| None |
+ |
100 |
81.7 ± 2.3 |
1.00 |
| MAK-5, 500 μg/ml plus MAK-4, 0 μg/ml |
+ |
65 |
25.3 ± 2.7 |
0.52 |
| MAK-5, 500 μg/ml plus MAK-4, 100 μg/ml |
+ |
81 |
17.7 ± 0.9 |
0.28 |
| MAK-5, 500 μg/ml plus MAK-4, 200 μg/ml |
+ |
88 |
20.3 ± 0.8 |
0.31 |
|
The experimental procedure and the duration of treatment was the same as Table 1. | ||||
Penza et al. BMC Complementary and Alternative Medicine 2007 7:19 doi:10.1186/1472-6882-7-19 |
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