|
Experiment A: Carrageenan edema and oral administration |
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| Drug |
Paw volume increase over time (ml ± SD) and effect (% of negative control) |
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|
|
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| 1 hr |
3 hr |
5 hr |
7 hr |
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|
|
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| Saline |
0.57 ± 0.14 |
0.98 ± 0.13 |
0.93 ± 0.14 |
0.79 ± 0.14 |
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| Arnica D4 |
0.46 ± 0.12 |
-18 |
0.98 ± 0.14 |
0 |
0.85 ± 0.12 |
-8 |
0.72 ± 0.11 |
-9 |
| Apis D4 |
0.42 ± 0.12 |
-26 |
0.90 ± 0.15 |
-8 |
0.77 ± 0.14 |
-17 |
0.65 ± 0.15 |
-18 |
| Atropa D4 |
0.44 ± 0.09 |
-22 |
0.94 ± 0.16 |
-4 |
0.80 ± 0.18 |
-14 |
0.73 ± 0.17 |
-7 |
| Hamamelis D4 |
0.49 ± 0.11 |
-14 |
0.88 ± 0.14 |
-10 |
0.78 ± 0.17 |
-16 |
0.68 ± 0.14 |
-14 |
| Lachesis D6 |
0.41 ± 0.10 |
-28 |
0.87 ± 0.18 |
-11 |
0.81 ± 0.17 |
-12 |
0.62 ± 0.18 |
-21 |
| Phosphorus D6 |
0.41 ± 0.13 |
-28 |
0.86 ± 0.14 |
-12 |
0.78 ± 0.13 |
-16 |
0.65 ± 0.11 |
-18 |
| Indomethacin i.m. |
0.38 ± 0.14 |
-34 |
0.63 ± 0.18 |
-36 |
0.59 ± 0.18 |
-36 |
0.49 ± 0.18 |
-38 |
|
ANOVA results. Treatment: F(7,136) = 8.38, p < 0.0001; Time: F(3,408) = 674.23, p < 0.0001; Treatment × time: F(21,408) = 3.65, p < 0.0001. Bold characters denote significant comparisons (by Student t test) vs. Saline group corresponding for time since edema induction. | ||||||||
Conforti et al. BMC Complementary and Alternative Medicine 2007 7:1 doi:10.1186/1472-6882-7-1 |
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