Table 1

General scheme of the study

Phase A

Phase B


Randomisation

by cages

within cages by treatments

-


Blinding

Treatment administration

-

Edema measurement


Inflammation model

CA

BL

CA


Homeopathic remedies

dilution

n. of animals studied


Arnica

D4

71

O/I

O/I

-

Apis

D4

90

O/I

O/I

O

Apis

D30

18

-

-

O

Atropa

D4

72

O/I

O/I

-

Hamamelis

D4

72

O/I

O/I

-

Lachesis

D6

86

O/I

O/I

O

Lachesis

D30

18

-

-

O

Phosphorus

D6

90

O/I

O/I

O

Phosphorus

D30

18

-

-

O

Reference treatments

Placebo:

Physiological solution

86

O/I

O/I

O

Active comparator:

Indomethacin

88

I/I

I/I

I


O = oral administration

I = administration through injection

CA = carrageenan induced edema

BL = autologous blood induced edema

Each treatment group has been tested through 3 replications. In each replication 6 rats were studied. In experiment A 11 rats were excluded from the analyses because of problems with edema induction.

Conforti et al. BMC Complementary and Alternative Medicine 2007 7:1   doi:10.1186/1472-6882-7-1

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