Table 1

Effects of GCBE and its constituents on body weight gain and accumulation of visceral fats

Content in diet (%)

Mean total food intake (g/body)

Initial body weight Day 0 (g)

Final body weight Day 14 (g)


Control

--

75.3

28.2 ± 0.6

37.5 ± 1.6

GCBE

0.5

80.0

27.3 ± 0.5

33.2 ± 0.6 *

1

75.5

26.9 ± 0.7

32.8 ± 1.2 **

Caffeine

0.05

74.9

27.0 ± 0.4

35.0 ± 1.0

0.1

74.3

26.6 ± 0.4

33.9 ± 0.7

Chlorogenic acid

0.15

81.3

27.3 ± 0.5

35.2 ± 0.5

0.3

76.5

26.4 ± 0.3

34.5 ± 0.5

Control

--

73.8

26.8 ± 0.4

34.6 ± 1.2

Orlistat

0.05

82.4

27.0 ± 0.2

35.0 ± 0.4

0.1

81.3

26.3 ± 0.2

34.2 ± 1.0


Content in diet (%)

Body weight gain (g)

Epididymal fat (mg)

Perirenal fat (mg)


Control

--

9.3 ± 0.4

605 ± 71

223 ± 39

GCBE

0.5

6.0 ± 0.1 *

393 ± 59*

106 ± 20 *

1

5.8 ± 0.2 *

448 ± 68

124 ± 23

Caffeine

0.05

8.0 ± 0.2

536 ± 57

146 ± 29

0.1

7.3 ± 0.2

491 ± 39

150 ± 20

Chlorogenic acid

0.15

7.9 ± 0.1

574 ± 48

173 ± 24

0.3

8.1 ± 0.1

605 ± 82

175 ± 25

Control

--

7.8 ± 0.9

588 ± 55

249 ± 60

Orlistat

0.05

8.1 ± 0.4

612 ± 56

251 ± 45

0.1

7.8 ± 0.9

481 ± 51 *

180 ± 33 *


Mice were fed non-purified diet (CE-2) containing each sample for 14 days. Each value represents the mean ± SE of 6 to 7 mice. The asterisks denote a significant differences from the control group, *:p < 0.05 and **: p < 0.01.

Shimoda et al. BMC Complementary and Alternative Medicine 2006 6:9   doi:10.1186/1472-6882-6-9

Open Data