Table 1

Effect of Hibiscus rosa sinensis on TBARS, GSH, SOD and catalase in rat heart

PARAMETERS

Control

IR

H1 BL

H1 IR

H2 BL

H2 IR

H3 BL

H3 IR

TBARS

nmole/g wet wt

46.2 ± 1.5

67.8 ± 3.4*

48.8 ± 2.4

74.1 ± 5.3

58.3 ± 2.6*

49.3 ± 1.9

63.6 ± 2.6*

57.8 ± 1.7

GSH

μg/g wet wt

320.3 ± 6.9

289.7 ± 2.4*

312.8 ± 4.6

279.3 ± 9.8

441.1 ± 2.9*

372.1 ± 2.9

375.3 ± 1.5*

271.2 ± 7.4

SOD

I.U/mg protein

2.8 ± 0.3

1.5 ± 0.5*

2.7 ± 0.6

2.5 ± 0.8

5.9 ± 0.6 *

4.2 ± 0.7

4.4 ± 0.8*

2.5 ± 1.1

CAT

I.U/mg protein

43.1 ± 5.3

30.6 ± 2.7

40.7 ± 5.8

37.8 ± 4.5

59.4 ± 1.6*

46.4 ± 4.3

50.1 ± 1.4*

35.6 ± 1.8

All values are expressed as Mean ± SE (n = 6).

*p < 0.001 vs Control (C) p < 0.001 vs IP IR (One way ANOVA)

Group Control (C) – Vehicle (saline) treated rats

Group IR – Vehicle-treated rat hearts, Saline-fed and 85 mg/kg isoproterenol injection

Group H1 BL – Rats treated with 125 mg/kg of flowers of Hibiscus rosa sinensis

Group H1 IR – 250 mg/kg of flowers of Hibiscus rosa sinensis treated rat hearts subjected to 85 mg/kg isoproterenol injection

Group H2 BL – Rats treated with 250 mg/kg of flowers of Hibiscus rosa sinensis

Group H2 IR – 250 mg/kg of flowers of Hibiscus rosa sinensis treated rat hearts subjected to 85 mg/kg isoproterenol injection

Group H3 BL – Rats treated with 500 mg/kg of flowers of Hibiscus rosa sinensis

Group H3 IR – 500 mg/kg of flowers of Hibiscus rosa sinensis treated rat hearts subjected to 85 mg/kg isoproterenol injection

Gauthaman et al. BMC Complementary and Alternative Medicine 2006 6:32   doi:10.1186/1472-6882-6-32