Figure 2.

Dose-dependent inhibition of glioma cell proliferation by Scutellaria baicalensis extract. Glioma cell lines from primary tumors (ME and DI) and recurrent (MER and DIR) tumors, as well as BCNU resistant (designated "Drug") glioma cell lines were cultured with various concentrations of S. baicalensis extract (0–200 μg/ml). After treatment, cells were incubated for 14 days to allow for colony growth. Colonies of at least 50 cells were counted using a 4% Giemsa stain. Results were normalized to the control (untreated cells). Data show means ± SD of 3 replicates.