Table 2

Effects of total chikusetsusaponins and orlistat (a lipase inhibitor) on fat excretion on day 3 in feces of mice fed a high-fat diet


Animal No.
Feces weight (g)
Triacyglycrol in feces (μmol/g feces)

Laboratory chow pellet
13
1.04 ± 0.017*
5.05 ± 0.70*
High-fat diet (HF)
13
0.14 ± 0.035
36.66 ± 1.03
HF +



1% Total chikusetsusaponins
7
0.26 ± 0.012*
41.64 ± 3.48
HF +



3% Total chikusetsusaponins
7
0.31 ± 0.049
53.42 ± 4.86*
HF +



0.025 % orlistat (lipase inhibitor)
7
0.22 ± 0.040
394.38 ± 65.39*

Values are means ± S.E. of 7 – 13 mice. * Significantly different from the high-fat diet group, P < 0.05.

Han et al. BMC Complementary and Alternative Medicine 2005 5:9   doi:10.1186/1472-6882-5-9