Table 2

Changes from baseline to 9 months in primary outcomes, bone mineral density (BMD) and bone turnover markers.

Variable

Randomized to

Usual Care (n = 43)

Randomized to

Tai Chi (n = 43)

Per Protocol

Tai Chi (n = 26)

Baseline

9 Months

Baseline

9 Months

Baseline

9 Months


BMD

Femoral Neck (mean ± SD) (g/cm2)

% change (median [Q1, Q3])

.692 ± .068

.685 ± .069

-0.85 [-2.58, 0.70]

.680 ± .063

.681 ± .063

-0.39 [-1.48, 1.02]

*p = 0.24

.685 ± .074

.688 ± .075

-0.23 [-0.64, 1.02]

*p = 0.05

Total Hip (mean ± SD) (g/cm2)

% change (median [Q1, Q3])

.837 ± .077

.835 ± .078

-0.64 [-1.39, 0.92]

.829 ± .073

.832 ± .074

0.23 [-1.12, 0.89]

*p = 0.26

.832 ± .079

.834 ± .079

0.35 [-1.20, 1.13]

*p = 0.32

Spine (mean ± SD) (g/cm2)

% change (median [Q1, Q3])

.901 ± .128

.891 ± .132

-1.27 [-2.67, 0.28]

.898 ± .070

.889 ± .069

-1.38 [-2.72, 0.99]

*p = 0.98

.898 ± .076

.894 ±.072

-1.21 [-1.95, 1.88]

*p = 0.38

Bone Turnover Markers

CTX (mean ± SD)

    (ng/ml)

% change (median [Q1, Q3])

.603 ± .231

.629 ± .310

2.05 [-15.33, 23.19]

.554 ± .259

.569 ± .248

0.68 [-17.94, 24.19]

*p = 0.99

.594 ± .30

.552 ± .266

-7.17 [-25.77, 12.56]

*p = 0.21

OSC (mean ± SD)

    (ng/ml)

% change (median [Q1, Q3])

15.52 ± 4.94

16.50 ± 4.82

4.30 [0.00, 11.80]

16.29 ± 6.01

16.38 ± 5.72

1.94 [-10.03, 12.87]

*p = 0.35

17.11 ± 7.02

16.23 ± 5.96

-3.55 [-13.61, 7.23]

*p = 0.03


* p-value for comparison with Usual Care based on the Wilcoxon rank sum test.

Baseline and 9 month values represent mean values ± standard deviations. Change scores are summarized with median values and 25th (Q1) and 75th (Q3) percentiles. P-values indicate comparisons between Usual Care ground and Tai Chi and Per Protocol groups, based on the Wilcoxon rank sum test.

Wayne et al. BMC Complementary and Alternative Medicine 2012 12:7   doi:10.1186/1472-6882-12-7

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