The protective effects of ginsenoside Rg1 against hypertension target-organ damage in spontaneously hypertensive rats
- Equal contributors
1 Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road #501, Shanghai, 201203, China
2 Shenyang Pharmaceutical University, Wenhua Road #103, Shenyang, 110016, China
3 Fudan University Shanghai Cancer Center, Dongan Road #270, Shanghai, 200023, China
4 School of Medicine, Shanghai Jiaotong University, Dongfang Road #1630, Shanghai, 200127, China
BMC Complementary and Alternative Medicine 2012, 12:53 doi:10.1186/1472-6882-12-53Published: 25 April 2012
Additional file 1:
Figure S1. The representative chromatogram of high-performance liquid chromatography for Rg1. Agilent 1100 HPLC system was used and the detection wavelength was set at 280 nm. The mobile phase consisted of (A) acetonitrile and (B) 0.05% aqueous trifluoroacetic acid (V/V), using a gradient elution of 2%-10% A at 0–7 min, 10%–30% A at 7–20 min, 23%–27% A at 20–35 min, and 27%–60% A at 35–50 min .
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Additional file 2:
Figure S2.13C NMR spectrum of Rg1 detected by Bruker AM-400 spectrometer.
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Additional file 3:
Figure S3. Structure elucidation of Rg1. (A) Chemical structure of Rg1. (B)13C NMR (100 MHz) spectral data for Rg1.
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Additional file 4:
Figure S4. Experimental protocol. Rg1 treatment was performed from week 9 to week 12.
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