Figure 2.

Principal component analysis comparing the influence of EGCG on 67LR versus the control gene. a) For the control gene, the impact of the drug treatment was dependent on whether a gene knockdown was applied (I) or not (II). b) For the 67LR gene, siRNA-induced downregulation altered the extent of its synergy with EGCG (I) and a new data cluster was separated from the samples solely treated with the 67lr-KD (II). When no knockdown was applied, EGCG did not affect the gene regulation (III) in accordance with Figure  3a. (Color code: black labels indicate samples containing EGCG, grey labels indicate no EGCG; Legend: EGCG = EGCG treatment, MEDIA = media control, NV = non-targeting virus, TV = targeting virus, 67lr-KD = 67LR knockdown, control-KD = control knockdown).

Müller and Pfaffl BMC Complementary and Alternative Medicine 2012 12:258   doi:10.1186/1472-6882-12-258
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