Table 4

Effect of test materials and propanolol (reference control) on mean arterial blood pressure of rats

Group

Dose

(mg/kg bw.)

Mean arterial pressure (mmHg)


Before induction of hypertension

After induction of hypertension

After treatment of hypertension


Normal

-

107 ± 3.1

110 ± 3.4

109 ± 2.7


Untreated control

-

108 ± 3.4

143 ± 2.7

151 ± 3.0


Propanolol-treated

10

110 ± 3.2

145 ± 3.1

116 ± 2.5*


CUR

1000

106 ± 0.4

145 ± 0.3

138 ± 0.5


3000

104 ± 0.3

146 ± 0.4

137 ± 0.4


5000

107 ± 0.3

148 ± 0.3

135 ± 0.4


ZO

1000

105 ± 0.3

144 ± 0.4

135 ± 0.5


3000

107 ± 0.4

147 ± 0.5

137 ± 0.3


5000

106 ± 0.3

148 ± 0.4

119 ± 0.3*


AL

1000

105 ± 0.3

148 ± 0.5

118 ± 0.4*


3000

107 ± 0.4

144 ± 0.4

120 ± 0.4*


5000

106 ± 0.3

148 ± 0.4

122 ± 0.3*


PC

100

103 ± 0.3

147 ± 0.3

134 ± 0.5


500

105 ± 0.4

149 ± 0.4

124 ± 0.4*


1000

105 ± 0.4

147 ± 0.4

125 ± 0.4*


PPF

1000

104 ± 0.3

145 ± 0.4

134 ± 0.3


2000

108 ± 0.4

146 ± 0.5

134 ± 0.4


4000

104 ± 0.4

143 ± 0.5

134 ± 0.5


Data are presented as mean ± SEM values

*Statistically significant difference with baseline by paired t-test:

sBP and dBP of ZO-treated group at high dose level (p < 0.001)

sBP and dBP of AL-treated group at all dose levels (p < 0.001)

sBP and dBP of PC-treated group at medium and high dose levels (p < 0.001)

sBP and dBP of propanolol-treated group (p < 0.001)

Plengsuriyakarn et al. BMC Complementary and Alternative Medicine 2012 12:23   doi:10.1186/1472-6882-12-23

Open Data