Table 2

Effect of test materials and propanolol on systolic (sBP) and diastolic (dBP) blood pressure of rats

Group

Dose

(mg/kg bw.)

Blood Pressure (mmHg)


Before induction of hypertension

After induction of hypertension

After treatment of hypertension


sBP

dBP

sBP

dBP

sBP

dBP


Normal

-

118 ± 0.4

81 ± 0.3

120 ± 0.3

82 ± 0.4

120 ± 0.3*

81 ± 0.4*


Untreated control

-

119 ± 0.5

80 ± 0.4

178 ± 0.4

128 ± 0.4

181 ± 0.6

137* ± 0.4


Propanolol-treated

10

120 ± 0.6

81 ± 0.3

177 ± 0.4

131 ± 0.5

135 ± 0.4*

95 ± 0.4*


CUR

1000

119 ± 0.5

82 ± 0.3

178 ± 0.3

130 ± 0.4

164 ± 0.4

126 ± 0.3


3000

119 ± 0.4

79 ± 0.4

180 ± 0.4

131 ± 0.5

152 ± 0.3

121 ± 0.4


5000

118 ± 0.4

78 ± 0.3

179 ± 0.4

130 ± 0.4

136 ± 0.4*

101 ± 0.4*


ZO

1000

119 ± 0.5

81 ± 0.3

178 ± 0.5

130 ± 0.5

168 ± 0.3

119 ± 0.3


3000

120 ± 0.5

80 ± 0.3

180 ± 0.4

129 ± 0.5

163 ± 0.5

120 ± 0.5


5000

120 ± 0.4

81 ± 0.4

181 ± 0.5

128 ± 0.4

162 ± 0.4

119 ± 0.4


AL

1000

121 ± 0.5

79 ± 0.4

180 ± 0.4

131 ± 0.5

155 ± 0.3

109 ± 0.4


3000

118 ± 0.4

82 ± 0.4

179 ± 0.5

126 ± 0.5

156 ± 0.4

105 ± 0.5


5000

119 ± 0.3

81 ± 0.3

177 ± 0.4

169 ± 0.4

134 ± 0.4*

98 ± 0.3*


PC

100

117 ± 0.3

79 ± 0.4

180 ± 0.4

127 ± 0.5

180 ± 0.5

126 ± 0.4


500

118 ± 0.4

81 ± 0.3

177 ± 0.3

129 ± 0.4

170 ± 0.4

122 ± 0.4


1000

120 ± 0.5

80 ± 0.4

179 ± 0.4

128 ± 0.4

139 ± 0.3*

113 ± 0.4*


PPF

1000

119 ± 0.4

82 ± 0.4

179 ± 0.4

131 ± 0.4

169 ± 0.5

117 ± 0.3


3000

120 ± 0.5

79 ± 0.4

180 ± 0.5

130 ± 3.3

162 ± 0.4

121 ± 0.4


4000

119 ± 0.4

80 ± 0.3

181 ± 0.5

128 ± 0.5

162 ± 0.4

120 ± 0.5


Data are presented as mean ± SEM values

*Statistically significant difference with baseline by paired t-test:

sBP and dBP of CUR-treated group at high dose level (p < 0.001)

sBP and dBP of AL-treated group at high dose level (p < 0.001)

sBP and dBP of PC-treated group at high dose level (p < 0.001)

sBP and dBP of propanolol-treated group at high dose level (p < 0.001)

Plengsuriyakarn et al. BMC Complementary and Alternative Medicine 2012 12:23   doi:10.1186/1472-6882-12-23

Open Data